ARHGAP44
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| Rho GTPase activating protein 44 | MIM:617716 | Ensembl:ENSG00000006740 | HGNC:HGNC:29096 | PA166048987 | 17p12 |
GO terms in ARHGAP44
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0006887 | exocytosis |
| BP | IEA | GO:0007165 | signal transduction |
| BP | IBA | GO:0032956 | regulation of actin cytoskeleton organization |
| BP | IEA | GO:0032956 | regulation of actin cytoskeleton organization |
| BP | IBA | GO:0035020 | regulation of Rac protein signal transduction |
| BP | IBA | GO:0035021 | negative regulation of Rac protein signal transduction |
| BP | IEA | GO:0035021 | negative regulation of Rac protein signal transduction |
| BP | IEA | GO:0043547 | positive regulation of GTPase activity |
| BP | TAS | GO:0051056 | regulation of small GTPase mediated signal transduction |
| BP | IBA | GO:0061001 | regulation of dendritic spine morphogenesis |
| BP | IEA | GO:0061001 | regulation of dendritic spine morphogenesis |
| BP | IBA | GO:0098886 | modification of dendritic spine |
| BP | IEA | GO:0098886 | modification of dendritic spine |
| BP | IBA | GO:0098887 | neurotransmitter receptor transport, endosome to postsynaptic membrane |
| BP | IEA | GO:0098887 | neurotransmitter receptor transport, endosome to postsynaptic membrane |
| CC | IBA | GO:0005622 | intracellular |
| CC | TAS | GO:0005829 | cytosol |
| CC | IBA | GO:0014069 | postsynaptic density |
| CC | IEA | GO:0030054 | cell junction |
| CC | IBA | GO:0031256 | leading edge membrane |
| CC | IDA | GO:0031256 | leading edge membrane |
| CC | IBA | GO:0043197 | dendritic spine |
| CC | IEA | GO:0043197 | dendritic spine |
| CC | IBA | GO:0048786 | presynaptic active zone |
| CC | IEA | GO:0055037 | recycling endosome |
| MF | IBA | GO:0005096 | GTPase activator activity |
| MF | TAS | GO:0005096 | GTPase activator activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IDA | GO:0005543 | phospholipid binding |
| MF | IBA | GO:0048365 | Rac GTPase binding |
| MF | IEA | GO:0048365 | Rac GTPase binding |
Gene expression in normal tissue: ARHGAP44
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ARHGAP44
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-162582 | Signal Transduction |
| reactome | R-HSA-194315 | Signaling by Rho GTPases |
| reactome | R-HSA-194840 | Rho GTPase cycle |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ARHGAP44
CLASSFICATION
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