CEPT1
Summary: This gene codes for a choline/ethanolaminephosphotransferase, which functions in the synthesis of choline- or ethanolamine- containing phospholipids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| choline/ethanolamine phosphotransferase 1 | MIM:616751 | Ensembl:ENSG00000134255 | HGNC:HGNC:24289 | PA134892657 | 1p13.3 |
GO terms in CEPT1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0004142 | diacylglycerol cholinephosphotransferase activity |
| MF | TAS | GO:0004142 | diacylglycerol cholinephosphotransferase activity |
| MF | IBA | GO:0004307 | ethanolaminephosphotransferase activity |
| MF | TAS | GO:0004307 | ethanolaminephosphotransferase activity |
| MF | IBA | GO:0016780 | phosphotransferase activity, for other substituted phosphate groups |
| MF | IEA | GO:0046872 | metal ion binding |
| CC | IBA | GO:0005789 | endoplasmic reticulum membrane |
| CC | TAS | GO:0005789 | endoplasmic reticulum membrane |
| CC | IBA | GO:0005794 | Golgi apparatus |
| CC | IEA | GO:0016021 | integral component of membrane |
| CC | IEA | GO:0031965 | nuclear membrane |
| BP | TAS | GO:0006629 | lipid metabolic process |
| BP | IBA | GO:0006646 | phosphatidylethanolamine biosynthetic process |
| BP | IEA | GO:0006646 | phosphatidylethanolamine biosynthetic process |
| BP | TAS | GO:0006646 | phosphatidylethanolamine biosynthetic process |
| BP | TAS | GO:0006656 | phosphatidylcholine biosynthetic process |
| BP | IEA | GO:0006657 | CDP-choline pathway |
Gene expression in normal tissue: CEPT1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CEPT1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| biocarta | pcsynthesispathway | phosphatidylcholine biosynthesis pathway |
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-1483191 | Synthesis of PC |
| reactome | R-HSA-1483206 | Glycerophospholipid biosynthesis |
| reactome | R-HSA-1483213 | Synthesis of PE |
| reactome | R-HSA-1483257 | Phospholipid metabolism |
| reactome | R-HSA-556833 | Metabolism of lipids |
| wikipathways | WP3933 | Kennedy pathway from Sphingolipids |
| wikipathways | WP3940 | One carbon metabolism and related pathways |
| smpdb | SMP00479 | Plasmalogen Synthesis |
| humancyc | PWY3O-450 | phosphatidylcholine biosynthesis |
| humancyc | PWY4FS-6 | phosphatidylethanolamine biosynthesis II |
| kegg | hsa00440 | Phosphonate and phosphinate metabolism - Homo sapiens (human) |
| kegg | hsa00564 | Glycerophospholipid metabolism - Homo sapiens (human) |
| kegg | hsa00565 | Ether lipid metabolism - Homo sapiens (human) |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CEPT1
CLASSFICATION
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