CHIC2
Summary: This gene encodes a member of the CHIC family of proteins. The encoded protein contains a cysteine-rich hydrophobic (CHIC) motif, and is localized to vesicular structures and the plasma membrane. This gene is associated with some cases of acute myeloid leukemia. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| cysteine rich hydrophobic domain 2 | MIM:604332 | Ensembl:ENSG00000109220 | HGNC:HGNC:1935 | PA26466 | 4q12 |
GO terms in CHIC2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | ND | GO:0008150 | biological_process |
| CC | ND | GO:0005575 | cellular_component |
| CC | IEA | GO:0005794 | Golgi apparatus |
| CC | IBA | GO:0005798 | Golgi-associated vesicle |
| CC | IBA | GO:0005886 | plasma membrane |
| CC | IDA | GO:0005886 | plasma membrane |
| CC | IDA | GO:0043231 | intracellular membrane-bounded organelle |
| MF | ND | GO:0003674 | molecular_function |
| MF | IPI | GO:0005515 | protein binding |
Gene expression in normal tissue: CHIC2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CHIC2
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD399 | Selumetinib | 2 |
| iGMDRD341 | Triacsin c | 2 |
| iGMDRD100 | Zebularine | 2 |
| iGMDRD780 | PP-30 | 2 |
| iGMDRD280 | CYTOCHALASIN B | 2 |
| iGMDRD451 | Serdemetan | 3 |
| iGMDRD513 | BML-259 | 1 |
| iGMDRD187 | BRD9876 | 1 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CHIC2
CLASSFICATION
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