CHIC2


Summary: This gene encodes a member of the CHIC family of proteins. The encoded protein contains a cysteine-rich hydrophobic (CHIC) motif, and is localized to vesicular structures and the plasma membrane. This gene is associated with some cases of acute myeloid leukemia. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
cysteine rich hydrophobic domain 2MIM:604332Ensembl:ENSG00000109220HGNC:HGNC:1935PA264664q12

GO terms in CHIC2


Term TypeEvidence TypeGO Term IDGO Des.
BPNDGO:0008150biological_process
CCNDGO:0005575cellular_component
CCIEAGO:0005794Golgi apparatus
CCIBAGO:0005798Golgi-associated vesicle
CCIBAGO:0005886plasma membrane
CCIDAGO:0005886plasma membrane
CCIDAGO:0043231intracellular membrane-bounded organelle
MFNDGO:0003674molecular_function
MFIPIGO:0005515protein binding

Gene expression in normal tissue: CHIC2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in CHIC2


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD399Selumetinib2
iGMDRD341Triacsin c2
iGMDRD100Zebularine2
iGMDRD780PP-302
iGMDRD280CYTOCHALASIN B2
iGMDRD451Serdemetan3
iGMDRD513BML-2591
iGMDRD187BRD98761

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CHIC2

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