Summary: This gene encodes a subunit of glutamate receptor channels. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity.[provided by RefSeq, Jan 2009].

glutamate ionotropic receptor delta type subunit 1MIM:610659Ensembl:ENSG00000182771HGNC:HGNC:4575PA2897010q23.1-q23.2

GO terms in GRID1

Term TypeEvidence TypeGO Term IDGO Des.
MFIEAGO:0004970ionotropic glutamate receptor activity
MFIEAGO:0005234extracellularly glutamate-gated ion channel activity
MFIBAGO:0008066glutamate receptor activity
MFIBAGO:1904315transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
BPIEAGO:0034220ion transmembrane transport
BPISSGO:0035176social behavior
BPIEAGO:0035235ionotropic glutamate receptor signaling pathway
BPIBAGO:0035249synaptic transmission, glutamatergic
BPIBAGO:0050804modulation of chemical synaptic transmission
BPIEAGO:0060079excitatory postsynaptic potential
CCIBAGO:0005886plasma membrane
CCIEAGO:0016021integral component of membrane
CCIEAGO:0030054cell junction
CCIBAGO:0045211postsynaptic membrane
CCIEAGO:0045211postsynaptic membrane
CCHDAGO:0070062extracellular exosome
CCIBAGO:0098839postsynaptic density membrane

Gene expression in normal tissue: GRID1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in GRID1

DatabasePathway IDPathway Des.
kegghsa04080Neuroactive ligand-receptor interaction - Homo sapiens (human)
wikipathwaysWP3584MECP2 and Associated Rett Syndrome

Gene-Drug: Aster Plot

Drug IDDrug NameModel Num.

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in GRID1