HTATSF1


Summary: The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Sep 2009].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
HIV-1 Tat specific factor 1MIM:300346Ensembl:ENSG00000102241HGNC:HGNC:5276PA29540Xq26.3

GO terms in HTATSF1


Term TypeEvidence TypeGO Term IDGO Des.
CCTASGO:0005634nucleus
CCIDAGO:0005654nucleoplasm
CCIBAGO:0005684U2-type spliceosomal complex
CCIBAGO:0005686U2 snRNP
BPIBAGO:0000398mRNA splicing, via spliceosome
BPIEAGO:0006351transcription, DNA-templated
BPTASGO:0006357regulation of transcription by RNA polymerase II
BPTASGO:0019079viral genome replication
BPTASGO:0032784regulation of DNA-templated transcription, elongation
MFHDAGO:0003723RNA binding
MFIBAGO:0003723RNA binding

Gene expression in normal tissue: HTATSF1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in HTATSF1


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in HTATSF1

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