HTATSF1
Summary: The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Sep 2009].
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
HIV-1 Tat specific factor 1 | MIM:300346 | Ensembl:ENSG00000102241 | HGNC:HGNC:5276 | PA29540 | Xq26.3 |
GO terms in HTATSF1
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
CC | TAS | GO:0005634 | nucleus |
CC | IDA | GO:0005654 | nucleoplasm |
CC | IBA | GO:0005684 | U2-type spliceosomal complex |
CC | IBA | GO:0005686 | U2 snRNP |
BP | IBA | GO:0000398 | mRNA splicing, via spliceosome |
BP | IEA | GO:0006351 | transcription, DNA-templated |
BP | TAS | GO:0006357 | regulation of transcription by RNA polymerase II |
BP | TAS | GO:0019079 | viral genome replication |
BP | TAS | GO:0032784 | regulation of DNA-templated transcription, elongation |
MF | HDA | GO:0003723 | RNA binding |
MF | IBA | GO:0003723 | RNA binding |
Gene expression in normal tissue: HTATSF1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in HTATSF1
Database | Pathway ID | Pathway Des. |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in HTATSF1