IGFL1


Summary: The protein encoded by this gene is a member of the insulin-like growth factor family of signaling molecules. The encoded protein is synthesized as a precursor protein and is proteolytically cleaved to form a secreted mature peptide. The mature peptide binds to a receptor, which in mouse was found on the cell surface of T cells. Increased expression of this gene may be linked to psoriasis. [provided by RefSeq, Aug 2016].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
IGF like family member 1MIM:610544Ensembl:ENSG00000188293HGNC:HGNC:24093PA14735792119q13.32

Gene Categories:

DRUGGABLE GENOME

GO terms in IGFL1


Term TypeEvidence TypeGO Term IDGO Des.
MFIBAGO:0005102signaling receptor binding
MFIPIGO:0005515protein binding
CCIBAGO:0005615extracellular space
CCIDAGO:0005615extracellular space

Gene expression in normal tissue: IGFL1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in IGFL1


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD133Lapatinib2

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in IGFL1

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