KLHL15
Summary: This gene encodes a member of the kelch-like family of proteins that share a common domain structure consisting of an N-terminal broad-complex, tramtrack, bric-a-brac/poxvirus and zinc finger domain and C-terminal kelch repeat motifs. The encoded protein may be involved in protein ubiquitination and cytoskeletal organization. [provided by RefSeq, Apr 2009].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| kelch like family member 15 | MIM:300980 | Ensembl:ENSG00000174010 | HGNC:HGNC:29347 | PA134934728 | Xp22.11 |
GO terms in KLHL15
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IDA | GO:0006511 | ubiquitin-dependent protein catabolic process |
| BP | IEA | GO:0016567 | protein ubiquitination |
| BP | IDA | GO:0071630 | nuclear protein quality control by the ubiquitin-proteasome system |
| BP | IDA | GO:2000042 | negative regulation of double-strand break repair via homologous recombination |
| CC | IDA | GO:0005634 | nucleus |
| CC | IDA | GO:0031463 | Cul3-RING ubiquitin ligase complex |
| MF | IPI | GO:0005515 | protein binding |
Gene expression in normal tissue: KLHL15
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in KLHL15
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in KLHL15
CLASSFICATION
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