MYO1F
Summary: Myosins are molecular motors that use the energy from ATP hydrolysis to generate force on actin filaments. The protein encoded by this gene is an unconventional myosin that may be involved in the intracellular movement of membrane-enclosed compartments. There is evidence to suggest that mutations in this gene can result in hearing loss. [provided by RefSeq, Jan 2017].
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
myosin IF | MIM:601480 | Ensembl:ENSG00000142347 | HGNC:HGNC:7600 | PA31402 | 19p13.2 |
GO terms in MYO1F
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
BP | IEA | GO:0007018 | microtubule-based movement |
BP | ND | GO:0008150 | biological_process |
CC | NAS | GO:0016461 | unconventional myosin complex |
MF | IEA | GO:0003777 | microtubule motor activity |
MF | NAS | GO:0003779 | actin binding |
MF | IEA | GO:0005516 | calmodulin binding |
MF | NAS | GO:0005524 | ATP binding |
MF | IEA | GO:0008017 | microtubule binding |
Gene expression in normal tissue: MYO1F
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in MYO1F
Database | Pathway ID | Pathway Des. |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in MYO1F