NCEH1
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| neutral cholesterol ester hydrolase 1 | MIM:613234 | Ensembl:ENSG00000144959 | HGNC:HGNC:29260 | PA165697847 | 3q26.31 |
Gene Categories:
DRUGGABLE GENOMEGO terms in NCEH1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IBA | GO:0009056 | catabolic process |
| BP | IEA | GO:0016042 | lipid catabolic process |
| BP | TAS | GO:0034383 | low-density lipoprotein particle clearance |
| CC | TAS | GO:0005789 | endoplasmic reticulum membrane |
| CC | HDA | GO:0016020 | membrane |
| CC | IEA | GO:0016021 | integral component of membrane |
| MF | TAS | GO:0004771 | sterol esterase activity |
| MF | IBA | GO:0016787 | hydrolase activity |
Gene expression in normal tissue: NCEH1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in NCEH1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-174824 | Plasma lipoprotein assembly, remodeling, and clearance |
| reactome | R-HSA-382551 | Transport of small molecules |
| reactome | R-HSA-8964038 | LDL clearance |
| reactome | R-HSA-8964043 | Plasma lipoprotein clearance |
| kegg | hsa04927 | Cortisol synthesis and secretion - Homo sapiens (human) |
| kegg | hsa04934 | Cushing,s syndrome - Homo sapiens (human) |
| kegg | hsa04976 | Bile secretion - Homo sapiens (human) |
| kegg | hsa04979 | Cholesterol metabolism - Homo sapiens (human) |
| wikipathways | WP2004 | miR-targeted genes in lymphocytes - TarBase |
| wikipathways | WP2005 | miR-targeted genes in muscle cell - TarBase |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in NCEH1
CLASSFICATION
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