PCBP3


Summary: This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. The protein encoded by this gene lacks the nuclear localization signals found in other subfamily members. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2017].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
poly(rC) binding protein 3MIM:608502Ensembl:ENSG00000183570HGNC:HGNC:8651PA3299021q22.3

GO terms in PCBP3


Term TypeEvidence TypeGO Term IDGO Des.
BPIEAGO:0000122negative regulation of transcription by RNA polymerase II
BPNASGO:0016071mRNA metabolic process
CCHDAGO:0005634nucleus
CCHDAGO:0005829cytosol
CCHDAGO:0070062extracellular exosome
MFIEAGO:0001227transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
MFIEAGO:0003690double-stranded DNA binding
MFHDAGO:0003723RNA binding
MFNASGO:0003723RNA binding
MFIEAGO:1990829C-rich single-stranded DNA binding

Gene expression in normal tissue: PCBP3

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in PCBP3


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in PCBP3

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