POGZ
Summary: The protein encoded by this gene appears to be a zinc finger protein containing a transposase domain at the C-terminus. This protein was found to interact with the transcription factor SP1 in a yeast two-hybrid system. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Aug 2010].
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
pogo transposable element derived with ZNF domain | MIM:614787 | Ensembl:ENSG00000143442 | HGNC:HGNC:18801 | PA38685 | 1q21.3 |
GO terms in POGZ
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
MF | ISA | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding |
MF | IEA | GO:0003677 | DNA binding |
MF | IPI | GO:0005515 | protein binding |
MF | IEA | GO:0046872 | metal ion binding |
CC | IDA | GO:0000790 | nuclear chromatin |
CC | IBA | GO:0005634 | nucleus |
CC | IDA | GO:0005634 | nucleus |
CC | IDA | GO:0005654 | nucleoplasm |
CC | IDA | GO:0005737 | cytoplasm |
CC | IDA | GO:0005829 | cytosol |
CC | IBA | GO:0035097 | histone methyltransferase complex |
BP | IEA | GO:0006357 | regulation of transcription by RNA polymerase II |
BP | IMP | GO:0007064 | mitotic sister chromatid cohesion |
BP | IBA | GO:0010468 | regulation of gene expression |
BP | IBA | GO:0016569 | covalent chromatin modification |
BP | IBA | GO:0031060 | regulation of histone methylation |
BP | IEA | GO:0051301 | cell division |
BP | IMP | GO:0051382 | kinetochore assembly |
Gene expression in normal tissue: POGZ
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in POGZ
Database | Pathway ID | Pathway Des. |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in POGZ