SDK1


Summary: The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains six immunoglobulin-like domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
sidekick cell adhesion molecule 1MIM:607216Ensembl:ENSG00000146555HGNC:HGNC:19307PA1349571887p22.2

GO terms in SDK1


Term TypeEvidence TypeGO Term IDGO Des.
BPISSGO:0007156homophilic cell adhesion via plasma membrane adhesion molecules
BPISSGO:0007416synapse assembly
BPISSGO:0010842retina layer formation
BPTASGO:0045216cell-cell junction organization
BPIEAGO:0048148behavioral response to cocaine
BPIEAGO:0060998regulation of dendritic spine development
CCTASGO:0005886plasma membrane
CCIEAGO:0016021integral component of membrane
CCIEAGO:0030054cell junction
CCISSGO:0045202synapse
MFISSGO:0042802identical protein binding

Gene expression in normal tissue: SDK1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in SDK1


DatabasePathway IDPathway Des.
reactomeR-HSA-1500931Cell-Cell communication
reactomeR-HSA-373756SDK interactions
reactomeR-HSA-421270Cell-cell junction organization
reactomeR-HSA-446728Cell junction organization

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD30917AAG2
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SDK1

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