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TADA1

Summary: TADA1L is a protein subunit of the human STAGA complex (SPT3; (MIM 602947)/TAF9 (MIM 600822)/GCN5 (MIM 602301) acetyltransferase complex), which is a chromatin-modifying multiprotein complex (Martinez et al., 2001 [PubMed 11564863]).[supplied by OMIM, Apr 2009].

Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
transcriptional adaptor 1	MIM:612763	Ensembl:ENSG00000152382	HGNC:HGNC:30631	PA165752724	1q24.1

Gene Categories:

HISTONE MODIFICATION

GO terms in TADA1

Term Type	Evidence Type	GO Term ID	GO Des.
BP	IEA	GO:0006351	transcription, DNA-templated
BP	IBA	GO:0006357	regulation of transcription by RNA polymerase II
BP	IBA	GO:0043966	histone H3 acetylation
BP	IDA	GO:0043966	histone H3 acetylation
BP	IEA	GO:1903508	positive regulation of nucleic acid-templated transcription
CC	IBA	GO:0000124	SAGA complex
CC	IDA	GO:0005634	nucleus
CC	IDA	GO:0005654	nucleoplasm
CC	IDA	GO:0005829	cytosol
CC	IDA	GO:0005925	focal adhesion
CC	IDA	GO:0030914	STAGA complex
MF	IBA	GO:0003713	transcription coactivator activity
MF	IDA	GO:0003713	transcription coactivator activity
MF	IBA	GO:0004402	histone acetyltransferase activity
MF	IDA	GO:0004402	histone acetyltransferase activity

Gene expression in normal tissue: TADA1

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Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in TADA1

Database	Pathway ID	Pathway Des.
reactome	R-HSA-3214847	HATs acetylate histones
reactome	R-HSA-3247509	Chromatin modifying enzymes
reactome	R-HSA-4839726	Chromatin organization

Gene-Drug: Aster Plot

Drug ID	Drug Name	Model Num.
iGMDRD748	PHA-665752	2

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TADA1

SITE

DATATYPES

CLASSFICATION

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