TOR1AIP1
Summary: This gene encodes a type 2 integral membrane protein that binds A- and B-type lamins. The encoded protein localizes to the inner nuclear membrane and may be involved in maintaining the attachment of the nuclear membrane to the nuclear lamina during cell division. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2016].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| torsin 1A interacting protein 1 | MIM:614512 | Ensembl:ENSG00000143337 | HGNC:HGNC:29456 | PA142670715 | 1q25.2 |
GO terms in TOR1AIP1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IDA | GO:0032781 | positive regulation of ATPase activity |
| BP | ISS | GO:0034504 | protein localization to nucleus |
| BP | IEA | GO:0071763 | nuclear membrane organization |
| CC | IDA | GO:0005634 | nucleus |
| CC | IEA | GO:0005637 | nuclear inner membrane |
| CC | IEA | GO:0016021 | integral component of membrane |
| CC | IDA | GO:0031965 | nuclear membrane |
| MF | IDA | GO:0001671 | ATPase activator activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0005521 | lamin binding |
| MF | IPI | GO:0008092 | cytoskeletal protein binding |
| MF | IPI | GO:0051117 | ATPase binding |
Gene expression in normal tissue: TOR1AIP1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in TOR1AIP1
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in TOR1AIP1
CLASSFICATION
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