iGMDRD169
Standard Name | CHEMBL | Pubchem CID | KEGG Drug ID | DRUGBANK ID | Drug Status | Drug targets (TTD) | Drug Type |
---|---|---|---|---|---|---|---|
Tacrolimus | CHEMBL269732 | 445643 | D08556 | DB00864 | Alone | DAP000162 | Small Molecule |
Drug Class:
Agents for Dermatitis, Excluding CorticosteroidsAnti-Bacterial AgentsAntineoplastic and Immunomodulating AgentsCalcineurin Inhibitor ImmunosuppressantCalcineurin InhibitorsCYP3A Substrates (Sensitive)Cytochrome P-450 CYP3A SubstratesCytochrome P-450 CYP3A4 SubstratesCytochrome P-450 CYP3A5 SubstratesCytochrome P-450 CYP3A7 SubstratesCytochrome P-450 Enzyme InhibitorsDermatologicalsEnzyme InhibitorsHyperglycemia-Associated AgentsImmunologic FactorsImmunosuppressive AgentsLactonesMacrocyclic CompoundsMacrolidesMisc. Skin and Mucous Membrane AgentsMyelosuppressive AgentsP-glycoprotein/ABCB1 InducersP-glycoprotein/ABCB1 InhibitorsP-glycoprotein/ABCB1 SubstratesPolycyclic CompoundsPolyketidesDrug Pathways:
MAPK signaling pathwayCellular senescenceOsteoclast differentiationNatural killer cell mediated cytotoxicityTh1 and Th2 cell differentiationTh17 cell differentiationT cell receptor signaling pathwayType I polyketide structuresDrug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
Gene ID | Gene Name | Model Num. |
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Gene in drug-gene network: Network Plot
![](image/drug_network_legends.png)
Models in Tacrolimus