iGMDRD581

Canonical SMILES: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F

InChI: InChI=1S/C25H17F2N5O3S/c1-35-25-23(32-36(33,34)24-5-3-18(26)12-21(24)27)11-17(13-29-25)15-2-4-22-20(10-15)19(7-8-28-22)16-6-9-30-31-14-16/h2-14,32H,1H3

InChI Key: CGBJSGAELGCMKE-UHFFFAOYSA-N

Loading, please wait...
Standard Name
CHEMBL
Pubchem CID
DRUGBANK ID
Drug Status
Drug Type
Standard NameOmipalisib
CHEMBLCHEMBL1236962
Pubchem CID25167800
DRUGBANK IDDB12703
Drug StatusAlone
Drug TypeSmall Molecule



Drug Pathways:

PI3K/MTOR signaling

Drug-model tissue-cancer distribution: Bubble Plot

SKItissue: SKI cancer: SKIN model num: 0SKINtissue: SKIN cancer: Melanoma (MEL) model num: 1

Drug-gene pathway enrichments

2reactome: Signalling to RAS2reactome: Signaling by NTRKs2reactome: Signaling by ERBB22reactome: Signal Transduction2reactome: Signaling by Receptor Tyrosine Kinases2reactome: GRB2 events in ERBB2 signaling2reactome: Signaling by NTRK1 (TRKA)2reactome: Signalling to ERKs2reactome: p38MAPK events1reactome: EGFR Transactivation by Gastrin

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Loading, please wait...
Gene ID
Gene Name
Model Num.
4893 NRAS 1
Showing 1 to 1 of 1 rows

Gene in drug-gene network: Network Plot

Models in Omipalisib

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​

SITE
DATATYPES
CLASSFICATION
Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.