iGMDRD784

Canonical SMILES: Cc1ccc(cc1NC(=O)C=C)N2C(=O)C=Cc3cnc4ccc(cc4c23)c5cn[nH]c5

InChI: InChI=1S/C25H19N5O2/c1-3-23(31)29-22-11-19(7-4-15(22)2)30-24(32)9-6-17-12-26-21-8-5-16(10-20(21)25(17)30)18-13-27-28-14-18/h3-14H,1H2,2H3,(H,27,28)(H,29,31)

InChI Key: JMVDIGHUQAXWIE-UHFFFAOYSA-N

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Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameQL-X-138
Pubchem CID73707500
Drug StatusAlone
Drug TypeSmall Molecule


Drug Pathways:

Other, kinases

Drug-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 2LYMPtissue: LYMP cancer: LYMPH model num: 0LYMPHtissue: LYMPH cancer: Diffuse Large B-Cell Lymphoma (DLBCL) model num: 1BONtissue: BON cancer: BONE model num: 0BONEtissue: BONE cancer: Acute Myeloid Leukemia (AML) model num: 1

Drug-gene pathway enrichments

2reactome: Signaling by NTRKs2reactome: Signaling by Receptor Tyrosine Kinases2reactome: Signalling to RAS2reactome: p38MAPK events2reactome: GRB2 events in ERBB2 signaling2reactome: Signaling by NTRK1 (TRKA)2reactome: Signal Transduction2reactome: Signalling to ERKs2reactome: Signaling by ERBB21reactome: Fc epsilon receptor (FCERI) signaling

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
9757 KMT2B 2
4893 NRAS 1
Showing 1 to 2 of 2 rows

Gene in drug-gene network: Network Plot

Models in QL-X-138

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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