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HER2 inhibitor
iGMDRD918
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Standard Name
Drug Status
Drug Type
Standard Name
HER2 inhibitor
Drug Status
Family
Drug Type
undefined
Drug Class:
Kinase Inhibitor
Protein Kinase Inhibitors
Antineoplastic Agents
Antineoplastic Agents, Phytogenic
Drug-model tissue-cancer distribution: Bubble Plot
BREAS
tissue: BREAS cancer: BREAST model num: 0
BREAST
tissue: BREAST cancer: Breast Carcinoma model num: 1
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Drug-gene pathway enrichments
2
reactome: GRB2 events in ERBB2 signaling
2
reactome: Signaling by Receptor Tyrosine Kinases
2
reactome: Signal Transduction
2
reactome: SHC1 events in ERBB2 signaling
2
reactome: Signaling by ERBB2
1
reactome: TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
1
reactome: Intracellular signaling by second messengers
1
biocarta: role of erbb2 in signal transduction and oncology
1
pid: a6b1 and a6b4 Integrin signaling
1
biocarta: trefoil factors initiate mucosal healing
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Drug-gene GO enrichments
4
MF: protein tyrosine kinase activity
3
CC: receptor complex
3
CC: plasma membrane
2
BP: transmembrane receptor protein tyrosine kinase signaling pathway
2
MF: transmembrane receptor protein tyrosine kinase activity
2
MF: transmembrane signaling receptor activity
2
MF: protein heterodimerization activity
1
CC: basal plasma membrane
1
CC: integral component of membrane
1
CC: endosome membrane
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Drug-Gene: Aster Plot
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Gene ID
Gene Name
Model Num.
2064
ERBB2
1
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4
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Gene in drug-gene network: Network Plot
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Models in HER2 inhibitor
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found
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