iGMDRD947

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Standard Name
Drug Status
Standard NameML334 diastereomer
Drug StatusAlone

Drug Targets:

KEAP1NFE2L2

Drug-model tissue-cancer distribution: Bubble Plot

OVARtissue: OVAR cancer: OVARY model num: 0OVARYtissue: OVARY cancer: undefined model num: 1PANCREAtissue: PANCREA cancer: PANCREAS model num: 0PANCREAStissue: PANCREAS cancer: undefined model num: 1

Drug-gene pathway enrichments

2reactome: Ubiquitin Mediated Degradation of Phosphorylated Cdc25A2reactome: G2/M Checkpoints2reactome: p53-Independent DNA Damage Response2reactome: p53-Independent G1/S DNA damage checkpoint2reactome: Cell Cycle Checkpoints2reactome: G1/S DNA Damage Checkpoints2reactome: G2/M DNA damage checkpoint2reactome: Cell Cycle1reactome: TP53 Regulates Transcription of DNA Repair Genes1reactome: Regulation of TP53 Activity through Phosphorylation

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
1111 CHEK1 1
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Gene in drug-gene network: Network Plot

Models in ML334 diastereomer

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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