GNPDA1
Summary: Glucosamine-6-phosphate deaminase (EC 3.5.99.6) is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium (Arreola et al., 2003 [PubMed 12965206]).[supplied by OMIM, Jan 2010].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:601798 Ensembl IDEnsembl:ENSG00000113552 HGNC IDHGNC:HGNC:4417 PHARMGKB IDPA28796 Map Location5q31.3 | |||||
GO terms in GNPDA1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0004342 | glucosamine-6-phosphate deaminase activity |
| MF | IMP | GO:0004342 | glucosamine-6-phosphate deaminase activity |
| MF | TAS | GO:0004342 | glucosamine-6-phosphate deaminase activity |
| MF | IPI | GO:0005515 | protein binding |
| BP | IEA | GO:0005975 | carbohydrate metabolic process |
| BP | IMP | GO:0006043 | glucosamine catabolic process |
Gene expression in normal tissue: GNPDA1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in GNPDA1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-70171 | Glycolysis |
| reactome | R-HSA-70326 | Glucose metabolism |
| reactome | R-HSA-71387 | Metabolism of carbohydrates |
| kegg | hsa00520 | Amino sugar and nucleotide sugar metabolism - Homo sapiens (human) |
| humancyc | GLUAMCAT-PWY | N-acetylglucosamine degradation I |
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in GNPDA1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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