CHAF1A

Summary: Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50, p60 (CHAF1B; MIM 601245), and p150 (CHAF1A) subunits that assembles histone octamers onto replicating DNA in vitro (Kaufman et al., 1995 [PubMed 7600578]).[supplied by OMIM, Mar 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namechromatin assembly factor 1 subunit A
OMIM IDMIM:601246
Ensembl IDEnsembl:ENSG00000167670
HGNC IDHGNC:HGNC:1910
PHARMGKB IDPA26446
Map Location19p13.3

Gene Categories:

DNA REPAIR

GO terms in CHAF1A


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IDA GO:0000790 nuclear chromatin
CC IBA GO:0005634 nucleus
CC IDA GO:0032991 protein-containing complex
CC IBA GO:0033186 CAF-1 complex
CC IDA GO:0033186 CAF-1 complex
BP IEA GO:0006260 DNA replication
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Gene expression in normal tissue: CHAF1A

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in CHAF1A


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Database
Pathway ID
Pathway Des.
wikipathways WP2002 miR-targeted genes in epithelium - TarBase
wikipathways WP2004 miR-targeted genes in lymphocytes - TarBase
wikipathways WP2509 Nanoparticle triggered autophagic cell death
biocarta btg2pathway btg family proteins and cell cycle regulation
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD68 Paclitaxel 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CHAF1A

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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