MFSD10
Summary: This gene encodes a member of the major facilitator superfamily of transporter proteins. The encoded protein likely functions in efflux of organic anions, including the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:610977 Ensembl IDEnsembl:ENSG00000109736 HGNC IDHGNC:HGNC:16894 PHARMGKB IDPA162395840 Map Location4p16.3 | |||||
GO terms in MFSD10
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0005215 | transporter activity |
| MF | TAS | GO:0008493 | tetracycline transmembrane transporter activity |
| MF | IDA | GO:0008514 | organic anion transmembrane transporter activity |
| BP | IEA | GO:0006915 | apoptotic process |
| BP | IEA | GO:0015904 | tetracycline transport |
| BP | IDA | GO:0043252 | sodium-independent organic anion transport |
Gene expression in normal tissue: MFSD10
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in MFSD10
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in MFSD10
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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