COQ7
Summary: The protein encoded by this gene is similar to a mitochondrial di-iron containing hydroxylase in Saccharomyces cerevisiae that is involved with ubiquinone biosynthesis. Mutations in the yeast gene lead to slower development and longer life span. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010].
Loading, please wait...
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:601683 Ensembl IDEnsembl:ENSG00000167186 HGNC IDHGNC:HGNC:2244 PHARMGKB IDPA26761 Map Location16p12.3 | |||||
GO terms in COQ7
Loading, please wait...
Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IBA | GO:0006744 | ubiquinone biosynthetic process |
| BP | IEA | GO:0006744 | ubiquinone biosynthetic process |
| BP | IBA | GO:0042775 | mitochondrial ATP synthesis coupled electron transport |
| BP | IEA | GO:0055114 | oxidation-reduction process |
| CC | IDA | GO:0005634 | nucleus |
| CC | IBA | GO:0005743 | mitochondrial inner membrane |
Gene expression in normal tissue: COQ7
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in COQ7
Loading, please wait...
Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-196854 | Metabolism of vitamins and cofactors |
| reactome | R-HSA-2142789 | Ubiquinol biosynthesis |
| reactome | R-HSA-8978934 | Metabolism of cofactors |
| humancyc | PWY-5872 | ubiquinol-10 biosynthesis |
| kegg | hsa00130 | Ubiquinone and other terpenoid-quinone biosynthesis - Homo sapiens (human) |
Gene-Drug: Aster Plot
Loading, please wait...
Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 1 |
Showing 1 to 1 of 1 rows
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in COQ7
Loading, please wait...
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.