CBSL
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| cystathionine-beta-synthase like | Ensembl:ENSG00000274276 | HGNC:HGNC:51829 | 21p12 |
GO terms in CBSL
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IEA | GO:0005634 | nucleus |
| CC | IBA | GO:0005737 | cytoplasm |
| CC | IEA | GO:0005737 | cytoplasm |
| BP | IBA | GO:0006535 | cysteine biosynthetic process from serine |
| BP | IEA | GO:0006535 | cysteine biosynthetic process from serine |
| BP | IEA | GO:0019343 | cysteine biosynthetic process via cystathionine |
| MF | IEA | GO:0004122 | cystathionine beta-synthase activity |
| MF | IBA | GO:0004124 | cysteine synthase activity |
| MF | IBA | GO:0020037 | heme binding |
| MF | IBA | GO:0030170 | pyridoxal phosphate binding |
| MF | IEA | GO:0046872 | metal ion binding |
Gene expression in normal tissue: CBSL
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CBSL
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| humancyc | HOMOCYSDEGR-PWY | cysteine biosynthesis/homocysteine degradation (trans-sulfuration) |
| humancyc | PWY-5328 | superpathway of methionine degradation |
| humancyc | PWY-6292 | cysteine biosynthesis |
| humancyc | PWY66-426 | hydrogen sulfide biosynthesis (trans-sulfuration) |
| kegg | hsa00260 | Glycine, serine and threonine metabolism - Homo sapiens (human) |
| kegg | hsa00270 | Cysteine and methionine metabolism - Homo sapiens (human) |
| wikipathways | WP3940 | One carbon metabolism and related pathways |
| smpdb | SMP00004 | Glycine and Serine Metabolism |
| smpdb | SMP00029 | Selenoamino Acid Metabolism |
| smpdb | SMP00033 | Methionine Metabolism |
| smpdb | SMP00177 | Cystathionine Beta-Synthase Deficiency |
| smpdb | SMP00179 | Dihydropyrimidine Dehydrogenase Deficiency (DHPD) |
| smpdb | SMP00214 | S-Adenosylhomocysteine (SAH) Hydrolase Deficiency |
| smpdb | SMP00221 | Methionine Adenosyltransferase Deficiency |
| smpdb | SMP00222 | Glycine N-methyltransferase Deficiency |
| smpdb | SMP00223 | Non Ketotic Hyperglycinemia |
| smpdb | SMP00242 | Dimethylglycine Dehydrogenase Deficiency |
| smpdb | SMP00244 | Sarcosinemia |
| smpdb | SMP00340 | Methylenetetrahydrofolate Reductase Deficiency (MTHFRD) |
| smpdb | SMP00341 | Hypermethioninemia |
| smpdb | SMP00455 | Homocysteine Degradation |
| smpdb | SMP00484 | Dimethylglycine Dehydrogenase Deficiency |
| smpdb | SMP00485 | Hyperglycinemia, non-ketotic |
| smpdb | SMP00514 | Gamma-cystathionase deficiency (CTH) |
| smpdb | SMP00515 | Homocystinuria, cystathionine beta-synthase deficiency |
| smpdb | SMP00570 | Homocystinuria-megaloblastic anemia due to defect in cobalamin metabolism, cblG complementation type |
| smpdb | SMP00721 | 3-Phosphoglycerate dehydrogenase deficiency |
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-1614603 | Cysteine formation from homocysteine |
| reactome | R-HSA-1614635 | Sulfur amino acid metabolism |
| reactome | R-HSA-2408508 | Metabolism of ingested SeMet, Sec, MeSec into H2Se |
| reactome | R-HSA-2408522 | Selenoamino acid metabolism |
| reactome | R-HSA-71291 | Metabolism of amino acids and derivatives |
| reactome | R-HSA-71291 | Metabolism of amino acids and derivatives |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CBSL
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.