LRRN2
Summary: The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| leucine rich repeat neuronal 2 | MIM:605492 | Ensembl:ENSG00000170382 | HGNC:HGNC:16914 | PA162394661 | 1q32.1 |
GO terms in LRRN2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | TAS | GO:0007155 | cell adhesion |
| BP | TAS | GO:0007165 | signal transduction |
| CC | IEA | GO:0016021 | integral component of membrane |
| MF | TAS | GO:0038023 | signaling receptor activity |
Gene expression in normal tissue: LRRN2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in LRRN2
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in LRRN2
CLASSFICATION
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