CIB1


Summary: This gene encodes a member of the EF-hand domain-containing calcium-binding superfamily. The encoded protein interacts with many other proteins, including the platelet integrin alpha-IIb-beta-3, DNA-dependent protein kinase, presenilin-2, focal adhesion kinase, p21 activated kinase, and protein kinase D. The encoded protein may be involved in cell survival and proliferation, and is associated with several disease states including cancer and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location

GO terms in CIB1


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IMP GO:0005509 calcium ion binding
MF IPI GO:0005515 protein binding
MF IEA GO:0008022 protein C-terminus binding
MF IMP GO:0008427 calcium-dependent protein kinase inhibitor activity
MF IPI GO:0017016 Ras GTPase binding
MF IEA GO:0019901 protein kinase binding
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Gene expression in normal tissue: CIB1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in CIB1


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 2
iGMDRD309 17AAG 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CIB1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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