CIB1
Summary: This gene encodes a member of the EF-hand domain-containing calcium-binding superfamily. The encoded protein interacts with many other proteins, including the platelet integrin alpha-IIb-beta-3, DNA-dependent protein kinase, presenilin-2, focal adhesion kinase, p21 activated kinase, and protein kinase D. The encoded protein may be involved in cell survival and proliferation, and is associated with several disease states including cancer and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:602293 Ensembl IDEnsembl:ENSG00000185043 HGNC IDHGNC:HGNC:16920 PHARMGKB IDPA38423 Map Location15q26.1 |
GO terms in CIB1
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
MF | IMP | GO:0005509 | calcium ion binding |
MF | IPI | GO:0005515 | protein binding |
MF | IEA | GO:0008022 | protein C-terminus binding |
MF | IMP | GO:0008427 | calcium-dependent protein kinase inhibitor activity |
MF | IPI | GO:0017016 | Ras GTPase binding |
MF | IEA | GO:0019901 | protein kinase binding |
Gene expression in normal tissue: CIB1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CIB1
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Database | Pathway ID | Pathway Des. |
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No matching records found |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in CIB1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
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No matching records found |