TACC2

Summary: Transforming acidic coiled-coil proteins are a conserved family of centrosome- and microtubule-interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is induced by erythropoietin and is thought to affect the progression of breast tumors. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nametransforming acidic coiled-coil containing protein 2
OMIM IDMIM:605302
Ensembl IDEnsembl:ENSG00000138162
HGNC IDHGNC:HGNC:11523
PHARMGKB IDPA36300
Map Location10q26.13

GO terms in TACC2


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IDA GO:0035257 nuclear hormone receptor binding
CC IDA GO:0005654 nucleoplasm
CC IBA GO:0005737 cytoplasm
CC IEA GO:0005815 microtubule organizing center
CC IDA GO:0005829 cytosol
CC IDA GO:0005886 plasma membrane
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Gene expression in normal tissue: TACC2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in TACC2


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TACC2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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