ZNF273


Summary: This gene is a member of the krueppel C2H2-type zinc-finger protein family and encodes a protein with 13 C2H2-type zinc fingers and a KRAB domain. This nuclear protein is involved in transcriptional regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
zinc finger protein 273MIM:604756Ensembl:ENSG00000198039HGNC:HGNC:13067PA376437q11.21

GO terms in ZNF273


Term TypeEvidence TypeGO Term IDGO Des.
BPIEAGO:0006351transcription, DNA-templated
BPIEAGO:0006357regulation of transcription by RNA polymerase II
CCIEAGO:0005634nucleus
MFISAGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFNASGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFIEAGO:0003677DNA binding
MFIPIGO:0005515protein binding
MFIEAGO:0046872metal ion binding

Gene expression in normal tissue: ZNF273

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in ZNF273


DatabasePathway IDPathway Des.
reactomeR-HSA-212436Generic Transcription Pathway
reactomeR-HSA-73857RNA Polymerase II Transcription
reactomeR-HSA-74160Gene expression (Transcription)

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259013

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ZNF273

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