GADD45G


Summary: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq, Jul 2008].

Loading, please wait...
Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location

GO terms in GADD45G


Loading, please wait...
Term Type
Evidence Type
GO Term ID
GO Des.
BP IBA GO:0000185 activation of MAPKKK activity
BP IDA GO:0000185 activation of MAPKKK activity
BP IEA GO:0006915 apoptotic process
BP IEA GO:0006950 response to stress
BP IEA GO:0007275 multicellular organism development
BP IEA GO:0030154 cell differentiation
Showing 1 to 6 of 15 rows rows per page

Gene expression in normal tissue: GADD45G

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in GADD45G


Loading, please wait...
Database
Pathway ID
Pathway Des.
kegg hsa04010 MAPK signaling pathway - Homo sapiens (human)
kegg hsa04068 FoxO signaling pathway - Homo sapiens (human)
kegg hsa04110 Cell cycle - Homo sapiens (human)
kegg hsa04115 p53 signaling pathway - Homo sapiens (human)
kegg hsa04210 Apoptosis - Homo sapiens (human)
kegg hsa04218 Cellular senescence - Homo sapiens (human)
Showing 1 to 6 of 27 rows rows per page

Gene-Drug: Aster Plot


Loading, please wait...
Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 1
Showing 1 to 1 of 1 rows

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in GADD45G

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​