FOXN3
Summary: This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
Nameforkhead box N3 OMIM IDMIM:602628 Ensembl IDEnsembl:ENSG00000053254 HGNC IDHGNC:HGNC:1928 PHARMGKB IDPA26460 Map Location14q31.3-q32.11 |
GO terms in FOXN3
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
BP | IEA | GO:0006351 | transcription, DNA-templated |
BP | IEA | GO:0006357 | regulation of transcription by RNA polymerase II |
BP | IGI | GO:0007095 | mitotic G2 DNA damage checkpoint |
BP | IDA | GO:0045892 | negative regulation of transcription, DNA-templated |
BP | IEA | GO:0097094 | craniofacial suture morphogenesis |
CC | IC | GO:0005634 | nucleus |
Gene expression in normal tissue: FOXN3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in FOXN3
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Database | Pathway ID | Pathway Des. |
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No matching records found |
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in FOXN3
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
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No matching records found |