CDC42EP1
Summary: CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin cytoskeleton reorganization at the plasma membrane. This protein is secreted and is primarily found in bone marrow. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:606084 Ensembl IDEnsembl:ENSG00000128283 HGNC IDHGNC:HGNC:17014 PHARMGKB IDPA38430 Map Location22q13.1 |
GO terms in CDC42EP1
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
MF | IPI | GO:0005515 | protein binding |
MF | IBA | GO:0017049 | GTP-Rho binding |
MF | HDA | GO:0098641 | cadherin binding involved in cell-cell adhesion |
CC | IBA | GO:0005737 | cytoplasm |
CC | IBA | GO:0005856 | cytoskeleton |
CC | IEA | GO:0005856 | cytoskeleton |
Gene expression in normal tissue: CDC42EP1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CDC42EP1
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Database | Pathway ID | Pathway Des. |
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No matching records found |
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD309 | 17AAG | 2 |
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in CDC42EP1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
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No matching records found |