CDC42EP1
Summary: CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin cytoskeleton reorganization at the plasma membrane. This protein is secreted and is primarily found in bone marrow. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:606084 Ensembl IDEnsembl:ENSG00000128283 HGNC IDHGNC:HGNC:17014 PHARMGKB IDPA38430 Map Location22q13.1 | |||||
GO terms in CDC42EP1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IPI | GO:0005515 | protein binding |
| MF | IBA | GO:0017049 | GTP-Rho binding |
| MF | HDA | GO:0098641 | cadherin binding involved in cell-cell adhesion |
| CC | IBA | GO:0005737 | cytoplasm |
| CC | IBA | GO:0005856 | cytoskeleton |
| CC | IEA | GO:0005856 | cytoskeleton |
Gene expression in normal tissue: CDC42EP1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CDC42EP1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD309 | 17AAG | 2 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CDC42EP1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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