CELF3


Summary: Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
CUGBP Elav-like family member 3MIM:612678Ensembl:ENSG00000159409HGNC:HGNC:11967PA366541q21.3

GO terms in CELF3


Term TypeEvidence TypeGO Term IDGO Des.
BPIBAGO:0000381regulation of alternative mRNA splicing, via spliceosome
BPIDAGO:0000381regulation of alternative mRNA splicing, via spliceosome
BPIBAGO:0006376mRNA splice site selection
BPIEAGO:0006397mRNA processing
BPIEAGO:0007283spermatogenesis
BPIMPGO:0008380RNA splicing
BPIEAGO:0030317flagellated sperm motility
BPIEAGO:0030575nuclear body organization
BPIDAGO:0048026positive regulation of mRNA splicing, via spliceosome
BPIEAGO:0098781ncRNA transcription
CCIBAGO:0005634nucleus
CCIDAGO:0005634nucleus
CCIBAGO:0005737cytoplasm
CCIDAGO:0005737cytoplasm
CCIEAGO:0016604nuclear body
MFIBAGO:0003723RNA binding
MFIMPGO:0003723RNA binding
MFIBAGO:0003729mRNA binding
MFNASGO:0036002pre-mRNA binding
MFIEAGO:00973227SK snRNA binding

Gene expression in normal tissue: CELF3

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in CELF3


DatabasePathway IDPathway Des.
wikipathwaysWP3527Preimplantation Embryo

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CELF3

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