CMTM7
Summary: This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor that regulates G1/S transition in the cell cycle, and epidermal growth factor receptor/protein kinase B signaling during tumor pathogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| CKLF like MARVEL transmembrane domain containing 7 | MIM:607890 | Ensembl:ENSG00000153551 | HGNC:HGNC:19178 | PA38817 | 3p22.3 |
GO terms in CMTM7
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0005125 | cytokine activity |
| BP | IEA | GO:0002337 | B-1a B cell differentiation |
| BP | IEA | GO:0006935 | chemotaxis |
| BP | IEA | GO:0010469 | regulation of signaling receptor activity |
| CC | IEA | GO:0005615 | extracellular space |
| CC | HDA | GO:0016020 | membrane |
| CC | IBA | GO:0016021 | integral component of membrane |
Gene expression in normal tissue: CMTM7
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CMTM7
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CMTM7
CLASSFICATION
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