CMTM7


Summary: This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor that regulates G1/S transition in the cell cycle, and epidermal growth factor receptor/protein kinase B signaling during tumor pathogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
CKLF like MARVEL transmembrane domain containing 7MIM:607890Ensembl:ENSG00000153551HGNC:HGNC:19178PA388173p22.3

GO terms in CMTM7


Term TypeEvidence TypeGO Term IDGO Des.
MFIEAGO:0005125cytokine activity
BPIEAGO:0002337B-1a B cell differentiation
BPIEAGO:0006935chemotaxis
BPIEAGO:0010469regulation of signaling receptor activity
CCIEAGO:0005615extracellular space
CCHDAGO:0016020membrane
CCIBAGO:0016021integral component of membrane

Gene expression in normal tissue: CMTM7

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in CMTM7


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259012

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CMTM7

​​​​