SYNRG


Summary: This gene encodes a protein that interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. This encoded protein may act to connect the AP1 complex to other proteins. Alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
synergin gammaMIM:607291Ensembl:ENSG00000275066HGNC:HGNC:557PA2484717q12

GO terms in SYNRG


Term TypeEvidence TypeGO Term IDGO Des.
CCTASGO:0005737cytoplasm
CCTASGO:0005794Golgi apparatus
CCTASGO:0030121AP-1 adaptor complex
BPTASGO:0006886intracellular protein transport
BPIEAGO:0006897endocytosis
MFIPIGO:0005515protein binding

Gene expression in normal tissue: SYNRG

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in SYNRG


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SYNRG

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