SYNRG
Summary: This gene encodes a protein that interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. This encoded protein may act to connect the AP1 complex to other proteins. Alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
Namesynergin gamma OMIM IDMIM:607291 Ensembl IDEnsembl:ENSG00000275066 HGNC IDHGNC:HGNC:557 PHARMGKB IDPA24847 Map Location17q12 | |||||
GO terms in SYNRG
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | TAS | GO:0005737 | cytoplasm |
| CC | TAS | GO:0005794 | Golgi apparatus |
| CC | TAS | GO:0030121 | AP-1 adaptor complex |
| BP | TAS | GO:0006886 | intracellular protein transport |
| BP | IEA | GO:0006897 | endocytosis |
| MF | IPI | GO:0005515 | protein binding |
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Gene expression in normal tissue: SYNRG
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SYNRG
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SYNRG
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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