SDSL
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| serine dehydratase like | Ensembl:ENSG00000139410 | HGNC:HGNC:30404 | PA134862016 | 12q24.13 |
GO terms in SDSL
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | ND | GO:0003674 | molecular_function |
| MF | IBA | GO:0003941 | L-serine ammonia-lyase activity |
| MF | IEA | GO:0003941 | L-serine ammonia-lyase activity |
| MF | IBA | GO:0004794 | L-threonine ammonia-lyase activity |
| MF | IEA | GO:0004794 | L-threonine ammonia-lyase activity |
| MF | TAS | GO:0016836 | hydro-lyase activity |
| MF | IEA | GO:0030170 | pyridoxal phosphate binding |
| MF | IPI | GO:0042802 | identical protein binding |
| BP | IBA | GO:0006565 | L-serine catabolic process |
| BP | IBA | GO:0006567 | threonine catabolic process |
| BP | ND | GO:0008150 | biological_process |
| BP | TAS | GO:0019518 | L-threonine catabolic process to glycine |
| CC | TAS | GO:0005829 | cytosol |
Gene expression in normal tissue: SDSL
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SDSL
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP4018 | Pathways in clear cell renal cell carcinoma |
| humancyc | PWY66-428 | threonine degradation |
| humancyc | SERDEG-PWY | L-serine degradation |
| kegg | hsa00260 | Glycine, serine and threonine metabolism - Homo sapiens (human) |
| kegg | hsa00270 | Cysteine and methionine metabolism - Homo sapiens (human) |
| kegg | hsa00290 | Valine, leucine and isoleucine biosynthesis - Homo sapiens (human) |
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-71291 | Metabolism of amino acids and derivatives |
| reactome | R-HSA-8849175 | Threonine catabolism |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SDSL
CLASSFICATION
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