FCHO2
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| FCH domain only 2 | MIM:613438 | Ensembl:ENSG00000157107 | HGNC:HGNC:25180 | PA134911830 | 5q13.2 |
GO terms in FCHO2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | ISS | GO:0001786 | phosphatidylserine binding |
| MF | IPI | GO:0005515 | protein binding |
| MF | IBA | GO:0005543 | phospholipid binding |
| MF | ISS | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding |
| MF | IBA | GO:0008017 | microtubule binding |
| MF | IBA | GO:0008092 | cytoskeletal protein binding |
| MF | IBA | GO:0015631 | tubulin binding |
| MF | ISS | GO:0035091 | phosphatidylinositol binding |
| MF | IEA | GO:0042802 | identical protein binding |
| BP | ISS | GO:0010324 | membrane invagination |
| BP | IBA | GO:0048268 | clathrin coat assembly |
| BP | IMP | GO:0048268 | clathrin coat assembly |
| BP | IBA | GO:0048488 | synaptic vesicle endocytosis |
| BP | IEA | GO:0048488 | synaptic vesicle endocytosis |
| BP | TAS | GO:0061024 | membrane organization |
| BP | IBA | GO:0072583 | clathrin-dependent endocytosis |
| BP | IMP | GO:0072583 | clathrin-dependent endocytosis |
| BP | ISS | GO:0072659 | protein localization to plasma membrane |
| BP | IBA | GO:0097320 | plasma membrane tubulation |
| CC | IBA | GO:0005737 | cytoplasm |
| CC | TAS | GO:0005829 | cytosol |
| CC | IBA | GO:0005856 | cytoskeleton |
| CC | IBA | GO:0005886 | plasma membrane |
| CC | ISS | GO:0005886 | plasma membrane |
| CC | IBA | GO:0005905 | clathrin-coated pit |
| CC | IDA | GO:0005905 | clathrin-coated pit |
| CC | IBA | GO:0030122 | AP-2 adaptor complex |
| CC | IBA | GO:0030136 | clathrin-coated vesicle |
| CC | IDA | GO:0030136 | clathrin-coated vesicle |
| CC | IBA | GO:0030139 | endocytic vesicle |
| CC | IEA | GO:0098835 | presynaptic endocytic zone membrane |
Gene expression in normal tissue: FCHO2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in FCHO2
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-199991 | Membrane Trafficking |
| reactome | R-HSA-5653656 | Vesicle-mediated transport |
| reactome | R-HSA-8856825 | Cargo recognition for clathrin-mediated endocytosis |
| reactome | R-HSA-8856828 | Clathrin-mediated endocytosis |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in FCHO2
CLASSFICATION
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