CATSPER1
Summary: Calcium ions play a primary role in the regulation of sperm motility. This gene belongs to a family of putative cation channels that are specific to spermatozoa and localize to the flagellum. The protein family features a single repeat with six membrane-spanning segments and a predicted calcium-selective pore region. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| cation channel sperm associated 1 | MIM:606389 | Ensembl:ENSG00000175294 | HGNC:HGNC:17116 | PA38438 | 11q13.1 |
GO terms in CATSPER1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0007275 | multicellular organism development |
| BP | IEA | GO:0007283 | spermatogenesis |
| BP | IEA | GO:0030154 | cell differentiation |
| BP | IEA | GO:0030317 | flagellated sperm motility |
| BP | IEA | GO:0034765 | regulation of ion transmembrane transport |
| BP | TAS | GO:0035036 | sperm-egg recognition |
| BP | IEA | GO:0070588 | calcium ion transmembrane transport |
| CC | TAS | GO:0005886 | plasma membrane |
| CC | IEA | GO:0031514 | motile cilium |
| CC | ISS | GO:0036128 | CatSper complex |
| MF | IEA | GO:0005227 | calcium activated cation channel activity |
| MF | IPI | GO:0005515 | protein binding |
Gene expression in normal tissue: CATSPER1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CATSPER1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1187000 | Fertilization |
| reactome | R-HSA-1300642 | Sperm Motility And Taxes |
| reactome | R-HSA-1474165 | Reproduction |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CATSPER1
CLASSFICATION
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