ANTXR2


Summary: This gene encodes a receptor for anthrax toxin. The protein binds to collagen IV and laminin, suggesting that it may be involved in extracellular matrix adhesion. Mutations in this gene cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].

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OMIM ID
Ensembl ID
HGNC ID
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GO terms in ANTXR2


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IBA GO:0007165 signal transduction
BP IEA GO:0007165 signal transduction
BP IEA GO:0022414 reproductive process
BP IBA GO:1901998 toxin transport
BP IEA GO:1901998 toxin transport
CC IEA GO:0005576 extracellular region
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Gene expression in normal tissue: ANTXR2

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 1

Gene-drug pathway distribution

ERK MAPK signaling1

Pathways in ANTXR2


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Database
Pathway ID
Pathway Des.
reactome R-HSA-1643685 Disease
reactome R-HSA-5210891 Uptake and function of anthrax toxins
reactome R-HSA-5339562 Uptake and actions of bacterial toxins
reactome R-HSA-5663205 Infectious disease
kegg hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)
pid anthraxpathway Cellular roles of Anthrax toxin
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ANTXR2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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