FOXN4

Summary: Members of the winged-helix/forkhead family of transcription factors, such as FOXN4, are characterized by a 110-amino acid DNA-binding domain that can fold into a variant of the helix-turn-helix motif consisting of 3 alpha helices flanked by 2 large loops or wings. These transcription factors are involved in a variety of biologic processes as key regulators in development and metabolism (Li et al., 2004 [PubMed 15363391]).[supplied by OMIM, Mar 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nameforkhead box N4
OMIM IDMIM:609429
Ensembl IDEnsembl:ENSG00000139445
HGNC IDHGNC:HGNC:21399
PHARMGKB IDPA134982965
Map Location12q24.11

GO terms in FOXN4


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Term Type
Evidence Type
GO Term ID
GO Des.
BP ISS GO:0001947 heart looping
BP IEA GO:0006351 transcription, DNA-templated
BP ISS GO:0006355 regulation of transcription, DNA-templated
BP IEA GO:0006357 regulation of transcription by RNA polymerase II
BP ISS GO:0008016 regulation of heart contraction
BP ISS GO:0010842 retina layer formation
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Gene expression in normal tissue: FOXN4

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 2

Gene-drug pathway distribution

Pathways in FOXN4


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in FOXN4

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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