OR2B11


Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].

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GO terms in OR2B11


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IEA GO:0004930 G-protein coupled receptor activity
MF IBA GO:0004984 olfactory receptor activity
BP IEA GO:0050911 detection of chemical stimulus involved in sensory perception of smell
CC TAS GO:0005886 plasma membrane
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Gene expression in normal tissue: OR2B11

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 2

Gene-drug pathway distribution

ERK MAPK signaling1

Pathways in OR2B11


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Database
Pathway ID
Pathway Des.
reactome R-HSA-162582 Signal Transduction
reactome R-HSA-372790 Signaling by GPCR
reactome R-HSA-381753 Olfactory Signaling Pathway
reactome R-HSA-388396 GPCR downstream signalling
reactome R-HSA-418555 G alpha (s) signalling events
kegg hsa04740 Olfactory transduction - Homo sapiens (human)
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in OR2B11

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No matching records found

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