CARNMT1
Summary: The protein encoded by this gene is a methyltransferase that converts carnosine to anserine, a dipeptide found abundantly in skeletal muscle. The encoded protein can methylate other dipeptides as well. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2016].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:616552 Ensembl IDEnsembl:ENSG00000156017 HGNC IDHGNC:HGNC:23435 PHARMGKB IDPA134929393 Map Location9q21.13 | |||||
GO terms in CARNMT1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0008757 | S-adenosylmethionine-dependent methyltransferase activity |
| MF | IBA | GO:0030735 | carnosine N-methyltransferase activity |
| MF | IDA | GO:0030735 | carnosine N-methyltransferase activity |
| MF | TAS | GO:0030735 | carnosine N-methyltransferase activity |
| CC | IBA | GO:0005634 | nucleus |
| CC | IDA | GO:0005634 | nucleus |
Gene expression in normal tissue: CARNMT1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CARNMT1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa00340 | Histidine metabolism - Homo sapiens (human) |
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-6788656 | Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism |
| reactome | R-HSA-70921 | Histidine catabolism |
| reactome | R-HSA-71291 | Metabolism of amino acids and derivatives |
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Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD309 | 17AAG | 2 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CARNMT1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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