CPNE8
Summary: Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
Namecopine 8 Ensembl IDEnsembl:ENSG00000139117 HGNC IDHGNC:HGNC:23498 PHARMGKB IDPA134980029 Map Location12q12 |
GO terms in CPNE8
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
BP | ND | GO:0008150 | biological_process |
BP | IBA | GO:0071277 | cellular response to calcium ion |
CC | IBA | GO:0005886 | plasma membrane |
CC | HDA | GO:0070062 | extracellular exosome |
MF | ND | GO:0003674 | molecular_function |
MF | IBA | GO:0005544 | calcium-dependent phospholipid binding |
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Gene expression in normal tissue: CPNE8
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CPNE8
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Database | Pathway ID | Pathway Des. |
---|---|---|
wikipathways | WP2002 | miR-targeted genes in epithelium - TarBase |
wikipathways | WP2004 | miR-targeted genes in lymphocytes - TarBase |
wikipathways | WP2005 | miR-targeted genes in muscle cell - TarBase |
wikipathways | WP2006 | miR-targeted genes in squamous cell - TarBase |
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Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD353 | PD0325901 | 2 |
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in CPNE8
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
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No matching records found |