NCAN

Summary: Neurocan is a chondroitin sulfate proteoglycan thought to be involved in the modulation of cell adhesion and migration.[supplied by OMIM, Jul 2002].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nameneurocan
OMIM IDMIM:600826
Ensembl IDEnsembl:ENSG00000130287
HGNC IDHGNC:HGNC:2465
PHARMGKB IDPA162396986
Map Location19p13.11

Gene Categories:

DRUGGABLE GENOME

GO terms in NCAN


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IEA GO:0005509 calcium ion binding
MF IEA GO:0030246 carbohydrate binding
BP IBA GO:0001501 skeletal system development
BP IEA GO:0007155 cell adhesion
BP IBA GO:0007417 central nervous system development
BP TAS GO:0030198 extracellular matrix organization
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Gene expression in normal tissue: NCAN

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

ERK MAPK signaling1

Pathways in NCAN


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Database
Pathway ID
Pathway Des.
wikipathways WP2431 Spinal Cord Injury
pid syndecan_3_pathway Syndecan-3-mediated signaling events
reactome R-HSA-1266738 Developmental Biology
reactome R-HSA-1430728 Metabolism
reactome R-HSA-1474244 Extracellular matrix organization
reactome R-HSA-1630316 Glycosaminoglycan metabolism
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in NCAN

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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