SEPT10
Summary: This gene encodes a member of the septin family of cytoskeletal proteins with GTPase activity. This protein localizes to the cytoplasm and nucleus and displays GTP-binding and GTPase activity. A pseudogene for this gene is located on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| septin 10 | MIM:611737 | Ensembl:ENSG00000186522 | HGNC:HGNC:14349 | PA134918683 | 2q13 |
GO terms in SEPT10
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0003924 | GTPase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0005525 | GTP binding |
| MF | IBA | GO:0032947 | protein-containing complex scaffold activity |
| BP | IBA | GO:0000281 | mitotic cytokinesis |
| BP | IBA | GO:0000921 | septin ring assembly |
| BP | IEA | GO:0007049 | cell cycle |
| BP | IBA | GO:0034613 | cellular protein localization |
| BP | IEA | GO:0051301 | cell division |
| BP | IBA | GO:0060271 | cilium assembly |
| CC | IEA | GO:0005737 | cytoplasm |
| CC | IEA | GO:0005856 | cytoskeleton |
| CC | IBA | GO:0005940 | septin ring |
| CC | IBA | GO:0015630 | microtubule cytoskeleton |
| CC | IBA | GO:0031105 | septin complex |
| CC | IBA | GO:0032153 | cell division site |
| CC | IBA | GO:0032160 | septin filament array |
Gene expression in normal tissue: SEPT10
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SEPT10
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SEPT10
CLASSFICATION
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