CNTN4


Summary: This gene encodes a member of the contactin family of immunoglobulins. Contactins are axon-associated cell adhesion molecules that function in neuronal network formation and plasticity. The encoded protein is a glycosylphosphatidylinositol-anchored neuronal membrane protein that may play a role in the formation of axon connections in the developing nervous system. Deletion or mutation of this gene may play a role in 3p deletion syndrome and autism spectrum disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
contactin 4MIM:607280Ensembl:ENSG00000144619HGNC:HGNC:2174PA266883p26.3-p26.2

Gene Categories:

DRUGGABLE GENOME

GO terms in CNTN4


Term TypeEvidence TypeGO Term IDGO Des.
BPTASGO:0007158neuron cell-cell adhesion
BPIMPGO:0007399nervous system development
BPTASGO:0007409axonogenesis
BPTASGO:0007411axon guidance
BPTASGO:0007413axonal fasciculation
BPISSGO:0007420brain development
BPISSGO:0031175neuron projection development
BPIMPGO:0045665negative regulation of neuron differentiation
BPTASGO:0048167regulation of synaptic plasticity
CCTASGO:0005576extracellular region
CCNASGO:0005886plasma membrane
CCTASGO:0005886plasma membrane
CCNASGO:0030424axon
CCIEAGO:0031225anchored component of membrane

Gene expression in normal tissue: CNTN4

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in CNTN4


DatabasePathway IDPathway Des.
reactomeR-HSA-163125Post-translational modification: synthesis of GPI-anchored proteins
reactomeR-HSA-392499Metabolism of proteins
reactomeR-HSA-597592Post-translational protein modification

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011
iGMDRD30917AAG1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CNTN4

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