| MF | IEA | GO:0004190 | aspartic-type endopeptidase activity |
| MF | IBA | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving |
| MF | IDA | GO:0042803 | protein homodimerization activity |
| BP | IBA | GO:0006465 | signal peptide processing |
| BP | IMP | GO:0006509 | membrane protein ectodomain proteolysis |
| BP | IMP | GO:0031293 | membrane protein intracellular domain proteolysis |
| BP | IBA | GO:0033619 | membrane protein proteolysis |
| CC | IBA | GO:0005765 | lysosomal membrane |
| CC | IDA | GO:0005789 | endoplasmic reticulum membrane |
| CC | IBA | GO:0030660 | Golgi-associated vesicle membrane |
| CC | IBA | GO:0071458 | integral component of cytoplasmic side of endoplasmic reticulum membrane |
| CC | IDA | GO:0071458 | integral component of cytoplasmic side of endoplasmic reticulum membrane |
| CC | IBA | GO:0071556 | integral component of lumenal side of endoplasmic reticulum membrane |
| CC | IDA | GO:0071556 | integral component of lumenal side of endoplasmic reticulum membrane |