DLG1
Summary: This gene encodes a multi-domain scaffolding protein that is required for normal development. This protein may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene, but the full-length nature of some of the variants is not known. [provided by RefSeq, Feb 2011].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:601014 Ensembl IDEnsembl:ENSG00000075711 HGNC IDHGNC:HGNC:2900 PHARMGKB IDPA27356 Map Location3q29 |
GO terms in DLG1
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
MF | TAS | GO:0004385 | guanylate kinase activity |
MF | TAS | GO:0004721 | phosphoprotein phosphatase activity |
MF | IPI | GO:0005515 | protein binding |
MF | IPI | GO:0008022 | protein C-terminus binding |
MF | TAS | GO:0008092 | cytoskeletal protein binding |
MF | TAS | GO:0015276 | ligand-gated ion channel activity |
Gene expression in normal tissue: DLG1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in DLG1
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Database | Pathway ID | Pathway Des. |
---|---|---|
reactome | R-HSA-112314 | Neurotransmitter receptors and postsynaptic signal transmission |
reactome | R-HSA-112315 | Transmission across Chemical Synapses |
reactome | R-HSA-112316 | Neuronal System |
reactome | R-HSA-1266738 | Developmental Biology |
reactome | R-HSA-373760 | L1CAM interactions |
reactome | R-HSA-399719 | Trafficking of AMPA receptors |
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD504 | Obatoclax | 1 |
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in DLG1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
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No matching records found |