DLG1


Summary: This gene encodes a multi-domain scaffolding protein that is required for normal development. This protein may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene, but the full-length nature of some of the variants is not known. [provided by RefSeq, Feb 2011].

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Name
OMIM ID
Ensembl ID
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GO terms in DLG1


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Term Type
Evidence Type
GO Term ID
GO Des.
MF TAS GO:0004385 guanylate kinase activity
MF TAS GO:0004721 phosphoprotein phosphatase activity
MF IPI GO:0005515 protein binding
MF IPI GO:0008022 protein C-terminus binding
MF TAS GO:0008092 cytoskeletal protein binding
MF TAS GO:0015276 ligand-gated ion channel activity
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Gene expression in normal tissue: DLG1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in DLG1


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Database
Pathway ID
Pathway Des.
reactome R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
reactome R-HSA-112315 Transmission across Chemical Synapses
reactome R-HSA-112316 Neuronal System
reactome R-HSA-1266738 Developmental Biology
reactome R-HSA-373760 L1CAM interactions
reactome R-HSA-399719 Trafficking of AMPA receptors
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD504 Obatoclax 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in DLG1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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