DTYMK
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| deoxythymidylate kinase | MIM:188345 | Ensembl:ENSG00000168393 | HGNC:HGNC:3061 | PA150 | 2q37.3 |
Gene Categories:
KINASEGO terms in DTYMK
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IBA | GO:0006227 | dUDP biosynthetic process |
| BP | IBA | GO:0006233 | dTDP biosynthetic process |
| BP | IBA | GO:0006235 | dTTP biosynthetic process |
| BP | IEA | GO:0006235 | dTTP biosynthetic process |
| BP | TAS | GO:0008283 | cell proliferation |
| BP | TAS | GO:0015949 | nucleobase-containing small molecule interconversion |
| BP | IEA | GO:0016310 | phosphorylation |
| BP | IEA | GO:0043627 | response to estrogen |
| BP | IEA | GO:0045445 | myoblast differentiation |
| BP | IEA | GO:0046686 | response to cadmium ion |
| BP | IEA | GO:0046940 | nucleoside monophosphate phosphorylation |
| BP | IEA | GO:0071363 | cellular response to growth factor stimulus |
| CC | IBA | GO:0005634 | nucleus |
| CC | IBA | GO:0005737 | cytoplasm |
| CC | IBA | GO:0005739 | mitochondrion |
| CC | IEA | GO:0005758 | mitochondrial intermembrane space |
| CC | IEA | GO:0005759 | mitochondrial matrix |
| CC | TAS | GO:0005829 | cytosol |
| MF | IBA | GO:0004798 | thymidylate kinase activity |
| MF | IDA | GO:0004798 | thymidylate kinase activity |
| MF | IEA | GO:0005524 | ATP binding |
| MF | IBA | GO:0009041 | uridylate kinase activity |
| MF | EXP | GO:0050145 | nucleoside monophosphate kinase activity |
Gene expression in normal tissue: DTYMK
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in DTYMK
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-15869 | Metabolism of nucleotides |
| reactome | R-HSA-499943 | Interconversion of nucleotide di- and triphosphates |
| kegg | hsa00240 | Pyrimidine metabolism - Homo sapiens (human) |
| pharmgkb | PA165859361 | Zidovudine Pathway, Pharmacokinetics/Pharmacodynamics |
| humancyc | PWY-7184 | pyrimidine deoxyribonucleotides de novo biosynthesis |
| humancyc | PWY-7197 | pyrimidine deoxyribonucleotide phosphorylation |
| humancyc | PWY-7200 | superpathway of pyrimidine deoxyribonucleoside salvage |
| humancyc | PWY-7210 | pyrimidine deoxyribonucleotides biosynthesis from CTP |
| humancyc | PWY-7211 | superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis |
| wikipathways | WP4022 | Pyrimidine metabolism |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in DTYMK
CLASSFICATION
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