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EEF1G

Summary: This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit contains an N-terminal glutathione transferase domain, which may be involved in regulating the assembly of multisubunit complexes containing this elongation factor and aminoacyl-tRNA synthetases. [provided by RefSeq, Jul 2008].

Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
eukaryotic translation elongation factor 1 gamma	MIM:130593	Ensembl:ENSG00000254772	HGNC:HGNC:3213	PA27649	11q12.3

GO terms in EEF1G

Term Type	Evidence Type	GO Term ID	GO Des.
MF	IBA	GO:0004364	glutathione transferase activity
MF	IPI	GO:0005515	protein binding
MF	HDA	GO:0045296	cadherin binding
CC	HDA	GO:0005634	nucleus
CC	IBA	GO:0005634	nucleus
CC	IBA	GO:0005737	cytoplasm
CC	IDA	GO:0005737	cytoplasm
CC	IDA	GO:0005783	endoplasmic reticulum
CC	TAS	GO:0005829	cytosol
CC	HDA	GO:0016020	membrane
CC	HDA	GO:0070062	extracellular exosome
BP	IBA	GO:0006414	translational elongation
BP	TAS	GO:0006414	translational elongation
BP	IBA	GO:0006749	glutathione metabolic process
BP	IEP	GO:0009615	response to virus

Gene expression in normal tissue: EEF1G

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Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in EEF1G

Database	Pathway ID	Pathway Des.
wikipathways	WP107	Translation Factors
kegg	hsa05134	Legionellosis - Homo sapiens (human)
reactome	R-HSA-156842	Eukaryotic Translation Elongation
reactome	R-HSA-392499	Metabolism of proteins
reactome	R-HSA-72766	Translation

Gene-Drug: Aster Plot

Drug ID	Drug Name	Model Num.
iGMDRD68	Paclitaxel	1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in EEF1G

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DATATYPES

CLASSFICATION

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