EEF1G

Summary: This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit contains an N-terminal glutathione transferase domain, which may be involved in regulating the assembly of multisubunit complexes containing this elongation factor and aminoacyl-tRNA synthetases. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nameeukaryotic translation elongation factor 1 gamma
OMIM IDMIM:130593
Ensembl IDEnsembl:ENSG00000254772
HGNC IDHGNC:HGNC:3213
PHARMGKB IDPA27649
Map Location11q12.3

GO terms in EEF1G


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IBA GO:0004364 glutathione transferase activity
MF IPI GO:0005515 protein binding
MF HDA GO:0045296 cadherin binding
CC HDA GO:0005634 nucleus
CC IBA GO:0005634 nucleus
CC IBA GO:0005737 cytoplasm
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Gene expression in normal tissue: EEF1G

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in EEF1G


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Database
Pathway ID
Pathway Des.
wikipathways WP107 Translation Factors
kegg hsa05134 Legionellosis - Homo sapiens (human)
reactome R-HSA-156842 Eukaryotic Translation Elongation
reactome R-HSA-392499 Metabolism of proteins
reactome R-HSA-72766 Translation
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD68 Paclitaxel 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in EEF1G

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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