FCER1G
Summary: The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:147139 Ensembl IDEnsembl:ENSG00000158869 HGNC IDHGNC:HGNC:3611 PHARMGKB IDPA28057 Map Location1q23.3 |
GO terms in FCER1G
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
BP | IEA | GO:0001798 | positive regulation of type IIa hypersensitivity |
BP | IEA | GO:0001805 | positive regulation of type III hypersensitivity |
BP | IEA | GO:0001812 | positive regulation of type I hypersensitivity |
BP | TAS | GO:0002223 | stimulatory C-type lectin receptor signaling pathway |
BP | IBA | GO:0002283 | neutrophil activation involved in immune response |
BP | IBA | GO:0002292 | T cell differentiation involved in immune response |
Gene expression in normal tissue: FCER1G
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in FCER1G
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Database | Pathway ID | Pathway Des. |
---|---|---|
reactome | R-HSA-109582 | Hemostasis |
reactome | R-HSA-114604 | GPVI-mediated activation cascade |
reactome | R-HSA-168249 | Innate Immune System |
reactome | R-HSA-168249 | Innate Immune System |
reactome | R-HSA-168256 | Immune System |
reactome | R-HSA-168256 | Immune System |
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD353 | PD0325901 | 2 |
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in FCER1G
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
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No matching records found |