FCER1G


Summary: The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location

GO terms in FCER1G


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IEA GO:0001798 positive regulation of type IIa hypersensitivity
BP IEA GO:0001805 positive regulation of type III hypersensitivity
BP IEA GO:0001812 positive regulation of type I hypersensitivity
BP TAS GO:0002223 stimulatory C-type lectin receptor signaling pathway
BP IBA GO:0002283 neutrophil activation involved in immune response
BP IBA GO:0002292 T cell differentiation involved in immune response
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Gene expression in normal tissue: FCER1G

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 2

Gene-drug pathway distribution

ERK MAPK signaling1

Pathways in FCER1G


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Database
Pathway ID
Pathway Des.
reactome R-HSA-109582 Hemostasis
reactome R-HSA-114604 GPVI-mediated activation cascade
reactome R-HSA-168249 Innate Immune System
reactome R-HSA-168249 Innate Immune System
reactome R-HSA-168256 Immune System
reactome R-HSA-168256 Immune System
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in FCER1G

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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